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Colorectal cancer (CRC), is the development of cancer from the colon or rectum colorectal cancers start as a growth on the inner lining of the colon.

What is Colorectal Cancer and Related FAQs

Following are some Colorectal Cancer or colon cancer Related FAQs

Q.1. What is Colorectal Cancer?

Ans. Colorectal cancer (CRC), is the development of cancer from the colon or rectum (parts of the large intestine).

Q.2. What is Cancer?

Ans. Cancer is when cells in the body start to grow out of control. Cells in nearly any part of the body can become cancer, and can spread to other areas of the body.

Q.3. How Does Colorectal Cancer Start?

Ans. Most colorectal cancers start as a growth on the inner lining of the colon or rectum. These growths are called polyps. Some types of polyps can change into cancer over time (usually many years), but not all polyps become cancer.

Q.4. Types of Cancer in the Colon and Rectum

Ans. Different types of colorectal cancers:-

  1. Adenocarcinomas (most common)
  2. Carcinoid tumors.
  3. Lymphomas
  4. Sarcomas

Q.5. Enumerate Factors that Can Increase a Person’s Risk of Colorectal Cancer?

Ans. Risk factors:-

  1. Overweight or obese
  2. Less physical activity
  3. Diet that’s high in red meats (such as beef, pork, lamb, or liver) and processed meats (like hot dogs and some luncheon meats)
  4. Smoked tobacco
  5. Heavy alcohol use
  6. Common after age 50
  7. History of inflammatory bowel disease or adenomatous polyp
  8. Family history of colorectal cancer or adenomatous polyp
  9. Rare inherited syndromes linked to colorectal cancer
  10. Type 2 diabetes

Q.5. Plethora in Treating Colorectal Cancer:

Ans. Different treatmnent arms for colorectal cancer:

  1. Treating Colorectal Cancer
  2. Ablation and Embolization for Colorectal Cancer
  3. Radiation Therapy
  4. Chemotherapy for Colorectal Cancer
  5. Targeted Therapy Drugs for Colorectal Cancer
  6. Immunotherapy for Colorectal Cancer
  7. Treatment of Colon Cancer, by Stage

Q.6. Immunotherapy For Colorectal Cancer:


– Pembrolizumab (Keytruda) target PD-1
– Nivolumab (Opdivo) target PD-1
– Ipilimumab (Yervoy) blocks CTLA-4

Immunotherapy is most advanced arm urrently in deciding treatment regimen of colorectal cancer even in the cases where cancer can’t be removed with surgery, has come back (recurred) after treatment, or has spread to other parts of the body (metastasized).

Also read:

Immunotherapy And Colon Cancer

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Dr Sajjan Rajpurohit

Best cancer specialist in Delhi, Dr. Sajjan Rajpurohit has been a practicing physician for the past 22 years and is currently working as Director in the Medical Oncology at BLK-Max Super Speciality Hospital, New Delhi. He is also a European certified as Best Medical Oncologist in Delhi, India, ESMO, Geneva. Dr. Sajjan Rajpurohit is acknowledged as a versatile veteran in treating various types of cancers. A qualified MBBS with MD in Medicine and DNB in Medical Oncology.